The first Clásico of the season will take place on Saturday 24 October at 16:00 CET, LaLiga have confirmed.
Madrid came out on top in the last meeting – winning 2-0 just before the Spanish football season was postponed back in March.
The last encounter at the Camp Nou finished scoreless, back in December 2019.
The time slot has reportedly chosen to suit global TV markets – taking place in the evening for viewers in Asia and the Far East, and in the morning for viewers across the United States, North America and South America.